PROTAC EGFR degrader 6 [2409793-28-6]
HY-146423
CAS Number2409793-28-6
Product group Chemicals
Molecular Weight913.05
Overview
- SupplierMedChem Express
- Product NamePROTAC EGFR degrader 6 [2409793-28-6]
- Delivery Days Customer10
- CAS Number2409793-28-6
- CertificationResearch Use Only
- Molecular FormulaC49H57FN12O5
- Molecular Weight913.05
- Scientific DescriptionPROTAC EGFR degrader 6, a PROTAC EGFR degrader, potently degrades EGFRDel19 in HCC827 cells with the DC50 of 45.2 nM. PROTAC EGFR degrader 6 significantly induces the apoptosis of HCC827 cells and arrest the cells in G1 phase[1].
- SMILESO=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=CC=C3NC(CCCCCCCN4CCN(CC4)C5=CC=C(N=C5)NC6=NC=C7N=C(N=C(C7=C6)N8CCC(CC8)CO)NC9=CC=C(C=C9)F)=O
- UNSPSC12131703