Bio-Connect

PROTAC EGFR degrader 6 [2409793-28-6]

HY-146423
MedChem Express
CAS Number2409793-28-6
Product group Chemicals
Molecular Weight913.05
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PROTAC EGFR degrader 6 [2409793-28-6]
  • Delivery Days Customer
    10
  • CAS Number
    2409793-28-6
  • Certification
    Research Use Only
  • Molecular Formula
    C49H57FN12O5
  • Molecular Weight
    913.05
  • Scientific Description
    PROTAC EGFR degrader 6, a PROTAC EGFR degrader, potently degrades EGFRDel19 in HCC827 cells with the DC50 of 45.2 nM. PROTAC EGFR degrader 6 significantly induces the apoptosis of HCC827 cells and arrest the cells in G1 phase[1].
  • SMILES
    O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=CC=C3NC(CCCCCCCN4CCN(CC4)C5=CC=C(N=C5)NC6=NC=C7N=C(N=C(C7=C6)N8CCC(CC8)CO)NC9=CC=C(C=C9)F)=O
  • UNSPSC
    12131703