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PROTAC HSP90 degrader BP3 [2669072-88-0]

HY-115997
MedChem Express
CAS Number2669072-88-0
Product group Chemicals
Estimated Purity99.54
Molecular Weight641.08
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PROTAC HSP90 degrader BP3 [2669072-88-0]
  • Delivery Days Customer
    10
  • CAS Number
    2669072-88-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.54
  • Molecular Formula
    C32H29ClN8O5
  • Molecular Weight
    641.08
  • Scientific Description
    PROTAC HSP90 degrader BP3 is a potent and selective degradation of HSP90 in a CRBN-dependent fashion. PROTAC HSP90 degrader BP3 has a certain degradation effect on HSP90 protein in MCF-7 cells (DC50=0.99 microM). PROTAC HSP90 degrader BP3 inhibits the growth of breast cancer cell[1]. PROTAC HSP90 degrader BP3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCC#CC4=CN(CC5=NC=C(C)C(OC)=C5C)C6=NC(N)=NC(Cl)=C64)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200