PROTAC IDO1 Degrader-1 [2488851-89-2]
T37329
Overview
- SupplierTargetMol Chemicals
- Product NamePROTAC IDO1 Degrader-1 [2488851-89-2]
- Delivery Days Customer999
- CAS Number2488851-89-2
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NamePROTAC IDO1 Degrader-1
- Molecular FormulaC40H53BrFN9O13
- Molecular Weight966.816
- Scientific DescriptionPROTAC IDO1 Degrader-1, a pioneering compound, efficiently targets indoleamine 2,3-dioxygenase 1 (IDO1) for ubiquitination and degradation by recruiting IDO1 to the CRBN E3 ligase, thereby facilitating its entry into the ubiquitin-proteasome system (UPS) with a DC50 of 2.84 microM. This compound also moderately enhances the tumor-killing efficacy of HER2 CAR-T cells[1].
- Shelf life instruction3 years
- SMILESO\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1NCCNCCOCCOCCOCCOCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
- Storage Instruction-20°C
- UNSPSC51202000
Related products
Product group Chemicals
PROTAC IDO1 Degrader-1HY-131911
CAS Number2488851-89-2
Estimated Purity99.00
Molecular Weight966.80
- SizePrice
Product group Chemicals
PROTAC IDO1 Degrader-1ORB1692981
CAS Number2488851-89-2
Estimated Purity98%
Molecular Weight966.816
- SizePrice