PROTAC JNK1-targeted-1

MedChem Express

PROTAC JNK1-targeted-1

5

Research Use Only

C35H32BrN9O6

754.59

PROTAC JNK1-targeted-1 (PA2) is a JNK1 PROTAC degrader, with a DC50 of 10 nM. PROTAC JNK1-targeted-1 (PA2) decreases the level of Fibronectin protein. PROTAC JNK1-targeted-1 can be used for the research of pulmonary fibrosis[1]. (Pink: JNK1 inhibitor (HY-170602); Black: linker (HY-40178); Blue: CRBN Ligand (HY-41547))

O=C(NCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C4=CC=C(NC5=NC=C(Br)C(NC6=CC=CC=C6C(N)=O)=N5)C=C4

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