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PROTAC K-Ras Degrader-1 [2378258-52-5]

Research Use Only
HY-129523
MedChem Express
CAS Number2378258-52-5
Product group Chemicals
Estimated Purity98.05
Molecular Weight999.12
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PROTAC K-Ras Degrader-1 [2378258-52-5]
  • Delivery Days Customer
    10
  • CAS Number
    2378258-52-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.05
  • Molecular Formula
    C53H62N10O10
  • Molecular Weight
    999.12
  • Scientific Description
    PROTAC K-Ras Degrader-1 (Compound 518) is a PROTAC. PROTAC K-Ras Degrader-1 can effectively degrades K-Ras based on Cereblon E3 ligand, exhibits ≥70% degradation efficacy in SW1573 cells[1].
  • SMILES
    CN1[C@@H](C[C@@H](OCCOCCOCCOCCNC2=C3C(C(N(C4C(NC(CC4)=O)=O)C3=O)=O)=CC=C2)C1)COC5=NC(N6C[C@@H](N(C(C=C)=O)CC6)CC#N)=C7C(CN(C8=CC=CC9=C8C=CC=C9)CC7)=N5
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200