PROTAC PARP1 degrader

Biorbyt

PROTAC PARP1 degrader

10

2369022-68-2

Research Use Only

98.00%

C58H63Cl2N11O10

1145.1

PROTAC PARP1 degrader is a degrader of PARP1 based on the PROTAC technology. PROTAC PARP1 degrader at 10 microM at 24 h inhibits MDA-MB-231 cell line (IC50 of 6.12 microM).

C(=O)(N1[C@]([C@](N=C1C2=C(OC(C)C)C=C(OC)C=C2)(C3=CC=C(Cl)C=C3)[H])(C4=CC=C(Cl)C=C4)[H])N5CC(=O)N(CC(NCCOCCOCCOCCOCCN6C=C(N=N6)C7=CC=C(C=C7)N8N=C9C(=C8)C=CC=C9C(N)=O)=O)CC5

-20°C

12352200