PROTAC Sirt2 Degrader-1 [2098487-75-1]
HY-103636
CAS Number2098487-75-1
Product group Chemicals
Estimated Purity98.5%
Molecular Weight852.94
Overview
- SupplierMedChem Express
- Product NamePROTAC Sirt2 Degrader-1 [2098487-75-1]
- Delivery Days Customer5
- CAS Number2098487-75-1
- CertificationResearch Use Only
- Estimated Purity98.5%
- Molecular FormulaC40H40N10O8S2
- Molecular Weight852.94
- Scientific DescriptionPROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 microM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 microM).
- SMILESO=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3OCC(NCCCCN4C=C(COC5=CC(CC6=CN=C(NC(CSC7=NC(C)=CC(C)=N7)=O)S6)=CC=C5)N=N4)=O
- Storage Instruction-20°C,-80°C
- UNSPSC12352200