PROTAC VEGFR-2 degrader-1 [2601594-19-6]

MedChem Express

PROTAC VEGFR-2 degrader-1 [2601594-19-6]

10

2601594-19-6

Research Use Only

C52H61N9O6S

940.16

PROTAC VEGFR-2 degrader-1 (PROTAC-1) , a PROTAC VEGFR-2 degrader, exhibits little VEGFR-2 inhibition (IC50> 1 microM) and anti-proliferative activity against EA.hy926 cells (IC50> 100 microM)[1].

O=C([C@H]1N(C([C@@H](NC(CCCCCC(N2N=C(N)C3=C2C=CC=C3C4=CC=CC(NC(NC5=CC=CC(C(C)C)=C5)=O)=C4)=O)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC6=CC=C(C7=C(C)N=CS7)C=C6

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