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Proteasome 20S beta 3 antibody [N1C3]

Research Use Only
GTX109566
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetPSMB3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Proteasome 20S beta 3 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.96 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID5691
  • Target name
    PSMB3
  • Target description
    proteasome 20S subunit beta 3
  • Target synonyms
    epididymis secretory sperm binding protein; HC10-II; proteasome (prosome, macropain) subunit, beta type, 3; proteasome chain 13; proteasome component C10-II; proteasome subunit beta 3; proteasome subunit beta type-3; proteasome theta chain
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP49720
  • Protein Name
    Proteasome subunit beta type-3
  • Scientific Description
    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells. Lin LL et al., 2015 Feb 5, BMC Genomics
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