Protein C antibody (Biotin)

GeneTex

Protein C antibody (Biotin)

9

Western Blot, ELISA

Research Use Only

Polyclonal

10 mg/ml

Biotin

Proc

protein C

anticoagulant protein C; autoprothrombin IIA; blood coagulation factor XIV; inactivator of coagulation factors Va, VIII; P; PC; vitamin K-dependent protein C

Sheep

IgG

This gene encodes the vitamin K-dependent protein C, which plays a vital role in the anticoagulation pathway. The encoded protein undergoes proteolytic processing including activation by thrombin-thrombomodulin complex to form the anticoagulant serine protease that degrades activated coagulation factors. A complete lack of the encoded protein in mice results in severe perinatal consumptive coagulopathy in the brain and liver, resulting in death within 24 hours after birth. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate the mature protein. [provided by RefSeq, Sep 2015]

Mouse

2°C to 8°C,-20°C or -80°C

12352203