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Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)

Research Use Only
TMPY-04406
TargetMol Chemicals
Product group Molecular Biology
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Scientific Description
    Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is widely expressed. It contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. PRKD2 / PKD2 is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains bind DAG, mediating translocation to membranes. Autophosphorylation of Ser-71 and phosphorylation of Ser-76 by PKC relieves auto-inhibition by the PH domain. PRKD2 / PKD2 converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352204