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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
CD278 [ICOS] (human):Fc (human) (rec.)
Catalog number:
CHI-HF-210ICOS-C025
Brand:
Chimerigen Laboratories
Packing:
25 ug
Other sizes:
Other size available
Price:
€ 165.00
Expected delivery time:
7 days
Quantity:
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General
Product specifications for - CD278 [ICOS] (human):Fc (human) (rec.)
Overview:
Product group:
Proteins / Signaling Molecule
Category:
Proteins
Species:
Human
Properties:
Purity:
>98% (SDS-PAGE)
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352202
Form supplied:
Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation. - Protein. The extracellular domain of human CD278 [ICOS] (aa 21-139) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/microg protein (LAL test; Lonza). Lyophilized from 0.2microm-filtered solution in PBS. Purity: >98% (SDS-PAGE). CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Safety information:
Hazard information:
Non-hazardous
Additional information:
Synonyms:
CHI-HF-210ICOS-C025; Chimerigen Laboratories