Bio-Connect

Prothionamide [14222-60-7]

HY-B0306
MedChem Express
CAS Number14222-60-7
Product group Chemicals
Estimated Purity99.94
Molecular Weight180.28
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Prothionamide [14222-60-7]
  • Delivery Days Customer
    5
  • CAS Number
    14222-60-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Hazard Information
    h302
  • Molecular Formula
    C9H12N2S
  • Molecular Weight
    180.28
  • Scientific Description
    Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 microM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 microg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy[1][2][3][4][5].
  • SMILES
    S=C(C1=CC(CCC)=NC=C1)N
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200