Protocadherin FAT2 (FAT Atypical Cadherin 2) (8C5), Biotin conjugate, 0.1mg/mL [26628-22-8]

Biotium

Protocadherin FAT2 (FAT Atypical Cadherin 2) (8C5), Biotin conjugate, 0.1mg/mL [26628-22-8]

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

8C5

0.1 mg/ml

Biotin

FAT2

FAT atypical cadherin 2

CDHF8, CDHR9, HFAT2, MEGF1, SCA45, protocadherin Fat 2, FAT tumor suppressor homolog 2, cadherin family member 8, cadherin-related family member 9, multiple EGF like domains 1, multiple EGF-like domains protein 1, multiple epidermal growth factor-like domains 1, multiple epidermal growth factor-like domains protein 1, protocadherin FAT2

Mouse

IgG1

Protocadherin Fat 2

This antibody recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2 -dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C,RT

41116161