Bio-Connect

Protocadherin Gamma (pan) Antibody: FITC

ORB150760
Biorbyt
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPcdhga1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Protocadherin Gamma (pan) antibody
  • Delivery Days Customer
    16
  • Application Supplier Note
    1 microg/ml of SMC-454 was sufficient for detection of Protocadherin gamma (pan) in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Applications Supplier
    WB (1:1000), ICC/IF (1:100) ICC, IF, IHC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    N159/5 (Formerly sold as S159-5)
  • Concentration
    1 mg/ml
  • Conjugate
    FITC
  • Gene ID93709
  • Target name
    Pcdhga1
  • Target description
    protocadherin gamma subfamily A, 1
  • Target synonyms
    protocadherin gamma-A1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ91XZ0
  • Protein Name
    MCG133388, isoform CRA_t
  • Scientific Description
    Mouse monoclonal to Protocadherin Gamma (FITC). The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes..
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    See Manual
  • UNSPSC
    12352203