Protocadherin Gamma (pan) Antibody: FITC
ORB150760
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPcdhga1
Overview
- SupplierBiorbyt
- Product NameProtocadherin Gamma (pan) antibody
- Delivery Days Customer16
- Application Supplier Note1 microg/ml of SMC-454 was sufficient for detection of Protocadherin gamma (pan) in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
- Applications SupplierWB (1:1000), ICC/IF (1:100) ICC, IF, IHC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDN159/5 (Formerly sold as S159-5)
- Concentration1 mg/ml
- ConjugateFITC
- Gene ID93709
- Target namePcdhga1
- Target descriptionprotocadherin gamma subfamily A, 1
- Target synonymsprotocadherin gamma-A1
- HostMouse
- IsotypeIgG1
- Protein IDQ91XZ0
- Protein NameMCG133388, isoform CRA_t
- Scientific DescriptionMouse monoclonal to Protocadherin Gamma (FITC). The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes..
- ReactivityHuman, Mouse, Rat
- Storage InstructionSee Manual
- UNSPSC12352203