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PRP8 antibody [C3-2], C-term

GTX108046
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetPRPF8
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Overview

  • Supplier
    GeneTex
  • Product Name
    PRP8 antibody [C3-2], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10594
  • Target name
    PRPF8
  • Target description
    pre-mRNA processing factor 8
  • Target synonyms
    220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; HPRP8; p220; precursor mRNA processing protein; pre-mRNA-processing-splicing factor 8; PRP8; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; PRPC8; RP13; SNRNP220; splicing factor Prp8; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ6P2Q9
  • Protein Name
    Pre-mRNA-processing-splicing factor 8
  • Scientific Description
    Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors. Moriel-Carretero M et al., 2017 Dec 4, J Cell Biol
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  • Argonaute proteins couple chromatin silencing to alternative splicing. Ameyar-Zazoua M et al., 2012 Oct, Nat Struct Mol Biol
    Read more