PRPS1 antibody [AT1E11]

GeneTex

PRPS1 antibody [AT1E11]

9

The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Western Blot, ELISA

Research Use Only

Monoclonal

AT1E11

1 mg/ml

Unconjugated

PRPS1

phosphoribosyl pyrophosphate synthetase 1

ARTS; CMTX5; deafness 2, perceptive, congenital; deafness, X-linked 2, perceptive, congenital; DFN2; DFNX1; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1); phosphoribosyl pyrophosphate synthase I; PPRibP; PRSI; PRS-I; ribose-phosphate diphosphokinase 1; ribose-phosphate pyrophosphokinase 1

Mouse

IgG2a

Ribose-phosphate pyrophosphokinase 1

This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

-20°C or -80°C,2°C to 8°C

12352203