PRR5 Polyclonal Antibody

Reddot Biotech

PRR5 Polyclonal Antibody

5

ImmunoFluorescence

Research Use Only

1 mg/ml

Unconjugated

PRR5

proline rich 5

FLJ20185k; PP610; proline rich 5 (renal); proline-rich protein 5; protein observed with Rictor-1; PROTOR1; PROTOR-1; Rho GTPase activating protein 8

Rabbit

IgG

This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

Human, Mouse, Rat

-20°C

12352203