PRT-060318 [1194961-19-7]
HY-12974
CAS Number1194961-19-7
Product group Chemicals
Estimated Purity99.59
Molecular Weight340.42
Overview
- SupplierMedChem Express
- Product NamePRT-060318 [1194961-19-7]
- Delivery Days Customer10
- CAS Number1194961-19-7
- CertificationResearch Use Only
- Estimated Purity99.59
- Hazard Informationh302-h315-h319-h335,p261-p264-p270-p271-p280-p302+p352-p304+p340-p305+p351+p338-p330-p362+p364-p403+p233-p405-p501
- Molecular FormulaC18H24N6O
- Molecular Weight340.42
- Scientific DescriptionPRT-060318 (PRT318) s a potent, selective and orally active tyrosine kinase Syk inhibitor with an IC50 of 3 nM. PRT-060318 suppresses chronic lymphocytic leukemia (CLL) B cell activation and migration, and induces apoptosis. PRT-060318 prevents Heparin (HY-17567)-induced thrombocytopenia and thrombosis in a transgenic mouse model. PRT-060318 dihydrochloride can be used for CLL and thrombus research[1][2].
- SMILESO=C(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=CC(C)=C3)N
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200

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