WB analysis of human brain tissue lysate in the (A) absence and (B) presence of blocking peptide using GTX85380 PRTFDC1 antibody. Working concentration : 1 microg/ml

PRTFDC1 antibody

Name: PRTFDC1 antibody
SKU: GTX85380_G10
Availability: BackOrder

GTX85380

ApplicationsWestern Blot, ELISA

DownloadDatasheet

Product group Antibodies

TargetPRTFDC1

Overview

Supplier
GeneTex
Product Name
PRTFDC1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID56952
Target name
PRTFDC1
Target description
phosphoribosyl transferase domain containing 1
Target synonyms
HHGP; phosphoribosyltransferase domain-containing protein 1
Host
Rabbit
Isotype
IgG
Protein IDQ9NRG1
Protein Name
Phosphoribosyltransferase domain-containing protein 1
Scientific Description
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

PRTFDC1 antibody

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Overview

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