Prucalopride (hydrochloride) [179474-80-7]
HY-14152
CAS Number179474-80-7
Product group Chemicals
Molecular Weight404.33
Overview
- SupplierMedChem Express
- Product NamePrucalopride (hydrochloride) [179474-80-7]
- Delivery Days Customer14
- CAS Number179474-80-7
- CertificationResearch Use Only
- Molecular FormulaC18H27Cl2N3O3
- Molecular Weight404.33
- Scientific DescriptionPrucalopride hydrochloride is an orally active, selective and specific 5-HT4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride hydrochloride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride hydrochloride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride hydrochloride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer[1][2][3].
- SMILESClC1=C(N)C(CCO2)=C2C(C(NC3CCN(CCCOC)CC3)=O)=C1.Cl
- UNSPSC12352200