Prucalopride (Standard) [179474-81-8]

HY-14151R
Product group Assays
Overview
- SupplierMedChem Express
- Product NamePrucalopride (Standard) [179474-81-8]
- Delivery Days Customer5
- CAS Number179474-81-8
- CertificationResearch Use Only
- Molecular FormulaC18H26ClN3O3
- Molecular Weight367.87
- Scientific DescriptionPrucalopride (Standard) is the analytical standard of Prucalopride. This product is intended for research and analytical applications. Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer[1][2][3].
- SMILESClC1=C(N)C(CCO2)=C2C(C(NC3CCN(CCCOC)CC3)=O)=C1
- UNSPSC41116135