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PRX I antibody [N1C2]

GTX101705
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPRDX1
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Overview

  • Supplier
    GeneTex
  • Product Name
    PRX I antibody [N1C2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.22 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5052
  • Target name
    PRDX1
  • Target description
    peroxiredoxin 1
  • Target synonyms
    MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, peroxiredoxin-1, epididymis secretory sperm binding protein, natural killer cell-enhancing factor A, natural killer-enhancing factor A, proliferation-associated gene A, proliferation-associated gene protein, thioredoxin peroxidase 2, thioredoxin-dependent peroxide reductase 2, thioredoxin-dependent peroxiredoxin 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ06830
  • Protein Name
    Peroxiredoxin-1
  • Scientific Description
    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Peng SY, Lin LC, Chen SR, et al. Pomegranate Extract (POMx) Induces Mitochondrial Dysfunction and Apoptosis of Oral Cancer Cells. Antioxidants (Basel). 2021,10(7). doi: 10.3390/antiox10071117
    Read this paper
  • Jadhao M, Tsai EM, Yang HC, et al. The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS. Antioxidants (Basel). 2021,10(6). doi: 10.3390/antiox10060949
    Read this paper
  • Liu W, Xu L, Wang X, et al. PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage. Autophagy. 2021,17(12):4159-4181. doi: 10.1080/15548627.2021.1905466
    Read this paper
  • Liu W, Wu CY, Lu MJ, et al. The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling. Oxid Med Cell Longev. 2020,2020:5167292. doi: 10.1155/2020/5167292
    Read this paper
  • Chou HC, Chan HL. Effect of glutathione reductase knockdown in response to UVB-induced oxidative stress in human lung adenocarcinoma. Proteome Sci. 2014,12(1):2. doi: 10.1186/1477-5956-12-2
    Read this paper
  • Chou HC, Chan HL. 5-Methoxytryptophan-dependent protection of cardiomyocytes from heart ischemia reperfusion injury. Arch Biochem Biophys. 2014,543:15-22. doi: 10.1016/j.abb.2013.12.014
    Read this paper
  • Fan CY, Chou HC, Lo YW, et al. Proteomic and redox-proteomic study on the role of glutathione reductase in human lung cancer cells. Electrophoresis. 2013,34(24):3305-14. doi: 10.1002/elps.201300250
    Read this paper
  • Ren P, Ye H, Dai L, et al. Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma. Oncol Rep. 2013,30(5):2297-303. doi: 10.3892/or.2013.2714
    Read this paper