IHC-P analysis of human prostatic hyperplasia tissue using GTX01887 PSA antibody [35H9]. Note the cytoplasmic and membrane staining of hyperplastic glandular epithelial cells.
PSA antibody [35H9]
GTX01887
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetKLK3
Overview
- SupplierGeneTex
- Product NamePSA antibody [35H9]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID35H9
- ConjugateUnconjugated
- Gene ID354
- Target nameKLK3
- Target descriptionkallikrein related peptidase 3
- Target synonymsAPS; gamma-seminoprotein; hK3; kallikrein-3; KLK2A1; P-30 antigen; prostate-specific antigen; PSA; semenogelase; seminin
- HostMouse
- IsotypeIgG1
- Scientific DescriptionKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203