Western blot analysis of extracts of various cell lines using PSAP Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using PSAP Polyclonal Antibody at dilution of 1:1000.
PSAP Polyclonal Antibody
E-AB-60459
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePSAP Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- UNSPSC12352203