PSMB10 antibody, Internal

GeneTex

PSMB10 antibody, Internal

9

WB: 0.3-1microg/ml. IHC-P: 5-10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

PSMB10

proteasome 20S subunit beta 10

beta2i; LMP10; low molecular mass protein 10; macropain subunit MECl-1; MECL1; multicatalytic endopeptidase complex subunit MECl-1; PRAAS5; proteasome (prosome, macropain) subunit, beta type, 10; proteasome catalytic subunit 2i; proteasome MECl-1; proteasome subunit beta 10; proteasome subunit beta 7i; proteasome subunit beta type-10; proteasome subunit beta2i; proteasome subunit beta-2i; proteasome subunit MECL1

Goat

IgG

Proteasome subunit beta type-10

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203