Western blot analysis of extracts of THP-1 cells using PSMB10 Polyclonal Antibody at dilution of 1:5000.
Western blot analysis of extracts of THP-1 cells using PSMB10 Polyclonal Antibody at dilution of 1:5000.
PSMB10 Polyclonal Antibody
E-AB-61800
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePSMB10 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.
- UNSPSC12352203