Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with PSPH antibody (GTX109163) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with PSPH antibody (GTX109163) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
PSPH antibody
GTX109163
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetPSPH
Overview
- SupplierGeneTex
- Product NamePSPH antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5723
- Target namePSPH
- Target descriptionphosphoserine phosphatase
- Target synonymsPSP, PSPHD, phosphoserine phosphatase, L-3-phosphoserine phosphatase, O-phosphoserine phosphohydrolase, PSPase
- HostRabbit
- IsotypeIgG
- Protein IDP78330
- Protein NamePhosphoserine phosphatase
- Scientific DescriptionThe protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- O'Leary EM, Tian Y, Nigdelioglu R, et al. TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation. Am J Respir Cell Mol Biol. 2020,63(5):601-612. doi: 10.1165/rcmb.2020-0143OCRead this paper
- Guo H, Xu J, Zheng Q, et al. NRF2 SUMOylation promotes de novo serine synthesis and maintains HCC tumorigenesis. Cancer Lett. 2019,466:39-48. doi: 10.1016/j.canlet.2019.09.010Read this paper
- Selvarajah B, Azuelos I, Platé M, et al. mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β(1)-induced collagen biosynthesis. Sci Signal. 2019,12(582). doi: 10.1126/scisignal.aav3048Read this paper
Datasheet
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