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PT2399 [1672662-14-4] [1672662-14-4]

PT2399 [1672662-14-4] [1672662-14-4]

T12675L
TargetMol Chemicals
CAS Number1672662-14-4
Product group Chemicals
Estimated Purity≥98%
Molecular Weight419.32
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PT2399 [1672662-14-4] [1672662-14-4]
  • Delivery Days Customer
    9
  • CAS Number
    1672662-14-4
  • Certification
    Research Use Only
  • Chemical Name
    PT2399
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C17H10F5NO4S
  • Molecular Weight
    419.32
  • Scientific Description
    PT2399 is a first-in-class, orally available, small molecule inhibitor of HIF-2 that selec
  • Shelf life instruction
    3 years
  • SMILES
    O[C@H]1c2c(CC1(F)F)c(Oc1cc(F)cc(c1)C#N)ccc2S(=O)(=O)C(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Design and Activity of Specific Hypoxia-Inducible Factor-2alpha (HIF-2alpha) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385).
    Read this paper