PT4 [1280738-47-7]
HY-146166
CAS Number1280738-47-7
Product group Chemicals
Molecular Weight318.33
Overview
- SupplierMedChem Express
- Product NamePT4 [1280738-47-7]
- Delivery Days Customer10
- CAS Number1280738-47-7
- CertificationResearch Use Only
- Molecular FormulaC18H14N4O2
- Molecular Weight318.33
- Scientific DescriptionPT4 is a therapeutic agent against Cutaneous leishmaniasis (CL). PT4 is effective against both species of Leishmania, with IC50s of 125.18 and 233.18 microM for L. amazonensis and L. braziliensis, respectively. PT4 decreases of mitochondrial membrane potential and increases production of reactive oxygen species, which leads to parasite death. PT4 has a potent in vivo anti-inflammatory activity[1].
- SMILESO=C1N(CCN2N=NC(C3=CC=CC=C3)=C2)C(C4=C1C=CC=C4)=O
- UNSPSC12131703