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PTC-028 [1782970-28-8]

PTC-028 [1782970-28-8]

Research Use Only
T16680
TargetMol Chemicals
CAS Number1782970-28-8
DownloadMSDS
Product group Chemicals
Estimated Purity98.25%
Molecular Weight405.32
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PTC-028 [1782970-28-8]
  • Delivery Days Customer
    4
  • CAS Number
    1782970-28-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PTC-028
  • Estimated Purity
    98.25%
  • Molecular Formula
    C19H12F5N5
  • Molecular Weight
    405.32
  • Scientific Description
    PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1nc2cc(F)c(F)cc2n1-c1cncc(Nc2ccc(cc2)C(F)(F)F)n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer. Dey A et al., 2018 Jan, Mol Cancer Ther
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