IHC-P analysis of human colon adenocarcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
![IHC-P analysis of human endometrium adenocarcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1815_IHC-P_w_23061420_189.webp "IHC-P analysis of human endometrium adenocarcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary adenocarcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1816_IHC-P_w_23061420_216.webp "IHC-P analysis of human ovary adenocarcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human liver carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1817_IHC-P_w_23061420_862.webp "IHC-P analysis of human liver carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human lung carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1818_IHC-P_w_23061420_363.webp "IHC-P analysis of human lung carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1819_IHC-P_w_23061420_357.webp "IHC-P analysis of human pancreas carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human thyroid carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1820_IHC-P_w_23061420_391.webp "IHC-P analysis of human thyroid carcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human endometrium tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1821_IHC-P_w_23061420_331.webp "IHC-P analysis of human endometrium tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human kidney tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1822_IHC-P_w_23061420_160.webp "IHC-P analysis of human kidney tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83771/GTX83771_1823_IHC-P_w_23061420_659.webp "IHC-P analysis of human pancreas tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
IHC-P analysis of human colon adenocarcinoma tissue using GTX83771 PTCH1 antibody [5c7]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
PTCH1 antibody [5c7]
GTX83771
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPTCH1
Overview
- SupplierGeneTex
- Product NamePTCH1 antibody [5c7]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. ICC/IF: 1:100. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5c7
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID5727
- Target namePTCH1
- Target descriptionpatched 1
- Target synonymsBCNS; NBCCS; protein patched homolog 1; PTC; PTC1; PTCH
- HostMouse
- IsotypeIgG2b
- Protein IDQ13635
- Protein NameProtein patched homolog 1
- Scientific DescriptionActs as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehogs proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Promoting roles of long non-coding RNA FAM83H-AS1 in bladder cancer growth, metastasis, and angiogenesis through the c-Myc-mediated ULK3 upregulation. Liu B et al., 2020 Dec, Cell CycleRead more
- Primary impact of Gli1 on radioresistance in esophageal cancer. Yao F et al., 2019 Nov, Oncol LettRead more
- Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex. Qi X et al., 2018 Oct 5, ScienceRead more
- Activities of the Cytoplasmic Domains of Patched-1 Modulate but Are Not Essential for the Regulation of Canonical Hedgehog Signaling. Fleet A et al., 2016 Aug 19, J Biol ChemRead more
Related products
Product group Antibodies
References
Goat anti-PTCH (C Terminus)EB07025
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
TargetPTCH1
- SizePrice
Product group Antibodies
ApplicationsImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetPTCH1
- SizePrice
Product group Antibodies
References
PTCH1 antibodyGTX108015
ApplicationsWestern Blot
TargetPTCH1
- SizePrice
Product group Antibodies
Anti-PTCH1 AntibodyHPA075072
ApplicationsImmunoCytoChemistry
TargetPTCH1
- SizePrice
Product group Antibodies
PTCH1 AntibodyCSB-PA040051
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
TargetPTCH1
- SizePrice
Product group Antibodies
ApplicationsWestern Blot, ImmunoHistoChemistry
TargetPTCH1
- SizePrice
Product group Antibodies
Patched AntibodyABX013172
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- SizePrice
Product group Antibodies
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- SizePrice