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PTCH1 antibody

Research Use Only
GTX108015
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetPTCH1
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    PTCH1 antibody
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.85 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5727
  • Target name
    PTCH1
  • Target description
    patched 1
  • Target synonyms
    BCNS; NBCCS; protein patched homolog 1; PTC; PTC1; PTCH
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Identification of novel GLI1 target genes and regulatory circuits in human cancer cells. Diao Y et al., 2018 Oct, Mol Oncol
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