PTP1B-IN-24

Biorbyt

PTP1B-IN-24

10

Research Use Only

98.00%

C22H16N2O5S

420.44

PTP1B-IN-24 (Compound 9), a reversible PTP1B inhibitor, exhibits an IC 50 value of 1.4 microM and can increase the thermal stability of PTP1B. This compound is capable of reversing PA-induced insulin resistance by enhancing the phosphorylation levels of IRS1 and AKT [1].

O=C1C=2C(OC=C1C=C3C(=O)N(CC(NC4=CC=C(C)C=C4)=O)C(=O)S3)=CC=CC2

-20°C

12352200