PTP1B/AKR1B1-IN-2

MedChem Express

PTP1B/AKR1B1-IN-2

14

Research Use Only

C23H23NO4S2

441.56

PTP1B/AKR1B1-IN-2 (Compound 7f) is a dual PTP1B/AKR1B1 inhibitor (IC50s: 3.2 and 2.1 microM, Kis: 4.0 and 0.9microM). PTP1B/AKR1B1-IN-2 is an insulin-mimetic agent. PTP1B/AKR1B1-IN-2 improves glucose uptake in murine C2C12 myoblasts. PTP1B/AKR1B1-IN-2 can be used for research of Type 2 diabetes mellitus (T2DM)[1].

O=C(CCN1C(/C(SC1=S)=C/C2=CC=CC(OCCCCC3=CC=CC=C3)=C2)=O)O

12131703