Western blot analysis of extracts of HeLa cells using PTPN2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of HeLa cells using PTPN2 Polyclonal Antibody at 1:1000 dilution.
PTPN2 Polyclonal Antibody
E-AB-60454
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePTPN2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.
- UNSPSC12352203