PTPN3 antibody

GeneTex

PTPN3 antibody

7

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

PTPN3

protein tyrosine phosphatase non-receptor type 3

cytoskeletal-associated protein tyrosine phosphatase; protein-tyrosine phosphatase H1; PTPH1; PTP-H1; tyrosine-protein phosphatase non-receptor type 3

Rabbit

IgG

Tyrosine-protein phosphatase non-receptor type 3

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

-20°C or -80°C,2°C to 8°C

12352203