
WB analysis of various sample lysates using GTX54572 PTPN3 antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane
PTPN3 antibody
GTX54572
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPTPN3
Overview
- SupplierGeneTex
- Product NamePTPN3 antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5774
- Target namePTPN3
- Target descriptionprotein tyrosine phosphatase non-receptor type 3
- Target synonymscytoskeletal-associated protein tyrosine phosphatase; protein-tyrosine phosphatase H1; PTPH1; PTP-H1; tyrosine-protein phosphatase non-receptor type 3
- HostRabbit
- IsotypeIgG
- Protein IDP26045
- Protein NameTyrosine-protein phosphatase non-receptor type 3
- Scientific DescriptionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling. Peng XS et al., 2020 Jun, Mol Cancer ResRead more