Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PTPRM Polyclonal Antibody at dilution 1:80
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PTPRM Polyclonal Antibody at dilution 1:80
PTPRM Polyclonal Antibody
E-AB-16045
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePTPRM Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration1.1mg/ml
- Scientific DescriptionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
- UNSPSC12352203