Sample (50 ug of whole cell lysate) A: mouse stomach 15% SDS PAGE GTX110549 diluted at 1:1000
![Wild-type (WT) and PTS knockout (KO) HeLa cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with PTS antibody [N1C3] (GTX110549) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX110549/GTX110549_40051_20180330_WB_KO_watremark_w_23060500_317.webp "Wild-type (WT) and PTS knockout (KO) HeLa cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with PTS antibody [N1C3] (GTX110549) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with PTS antibody [N1C3] (GTX110549) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX110549/GTX110549_40051_20181221_WB_B_w_23060500_235.webp "Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with PTS antibody [N1C3] (GTX110549) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
Sample (50 ug of whole cell lysate) A: mouse stomach 15% SDS PAGE GTX110549 diluted at 1:1000
PTS antibody [N1C3]
GTX110549
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPTS
Overview
- SupplierGeneTex
- Product NamePTS antibody [N1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5805
- Target namePTS
- Target description6-pyruvoyltetrahydropterin synthase
- Target synonymsPTPS, 6-pyruvoyl tetrahydrobiopterin synthase, PTP synthase
- HostRabbit
- IsotypeIgG
- Protein IDQ03393
- Protein Name6-pyruvoyl tetrahydrobiopterin synthase
- Scientific DescriptionThe enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ishikawa T, Imamura K, Kondo T, et al. Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders. Hum Mol Genet. 2016,25(23):5188-5197. doi: 10.1093/hmg/ddw339Read this paper
Datasheet
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