PU-H54

MedChem Express

PU-H54 [1454619-13-6]

10

1454619-13-6

Research Use Only

99.04

C18H19N5S

337.44

PU-H54, a Grp94-selective inhibitor, can be used for the research of breast cancer. Hsp90 chaperone family, comprised in humans of four paralogs, Hsp90alpha, Hsp90beta, Grp94 and Trap-1, has important roles in malignancy[1]. PU-H54 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

NC1=C2N=C(SC3=CC=C(C)C=C3C)N=C2N(CCCC#C)C=N1

-20°C,2°C to 8°C

12352200