PU3 [352519-21-2]
HY-121881
CAS Number352519-21-2
Product group Chemicals
Molecular Weight371.43
Overview
- SupplierMedChem Express
- Product NamePU3 [352519-21-2]
- Delivery Days Customer5
- CAS Number352519-21-2
- CertificationResearch Use Only
- Molecular FormulaC19H25N5O3
- Molecular Weight371.43
- Scientific DescriptionPU3 is an Hsp90 inhibitor that competes with geldanamycin (GM) and others for the conserved ATP/ADP pocket of Hsp90. PU3 also induces degradation of proteins such as Her2 and inhibits breast cancer cell growth by causing retinoblastoma protein hypophosphorylation, G1 arrest, and cell differentiation. PU3 has the potential to be a cancer inhibitor.[1].
- SMILESNC1=C2N=C(N(C2=NC=N1)CCCC)CC3=CC(OC)=C(C(OC)=C3)OC
- UNSPSC12352200