PUF60 antibody [GT677]

GeneTex

PUF60 antibody [GT677]

9

WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

GT677

1 mg/ml

Unconjugated

PUF60

poly(U) binding splicing factor 60

FIR, RoBPI, SIAHBP1, VRJS, poly(U)-binding-splicing factor PUF60, FBP interacting repressor, FUSE-binding protein-interacting repressor, Ro ribonucleoprotein-binding protein 1, Siah binding protein 1, poly(U) binding splicing factor 60KDa, pyrimidine tract binding splicing factor

Mouse

IgG2a

Poly(U)-binding-splicing factor PUF60

The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203