Purfalcamine [1038620-68-6]

MedChem Express

Purfalcamine [1038620-68-6]

10

1038620-68-6

Research Use Only

99.44

C29H33FN8O

528.62

Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage[1][2].

O=C(C1=CC=C(NC2=C3N=CN(C4=CC=CC(F)=C4)C3=NC(N[C@H]5CC[C@H](N)CC5)=N2)C=C1)N6CCCCC6

-20°C,2°C to 8°C

12352200