Purified Anti-Mouse CD132 Antibody
RD20287F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetIl2rg
Overview
- SupplierReddot Biotech
- Product NamePurified Anti-Mouse CD132 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID16186
- Target nameIl2rg
- Target descriptioninterleukin 2 receptor, gamma chain
- Target synonymsCD132, [g]c, gamma(c), gc, p64, cytokine receptor common subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, common gamma chain, gamma C receptor, interleukin-2 receptor subunit gamma
- HostRat
- IsotypeIgG2b
- Scientific DescriptionCD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common Oe≥ chain (Oe≥c) or IL-2 receptor Oe≥ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
