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Purified Anti-Mouse CD209b Antibody

Research Use Only
RD20384F
Reddot Biotech
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetCd209b
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    Purified Anti-Mouse CD209b Antibody
  • Delivery Days Customer
    5
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    22D1
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID69165
  • Target name
    Cd209b
  • Target description
    CD209b antigen
  • Target synonyms
    1810030I22Rik; CD209 antigen-like protein B; DC-SIGNR1; DC-SIGN-related protein 1; mSI; mSIGNR1; OtB7; SI; SIGNR1
  • Host
    Hamster
  • Isotype
    IgG
  • Scientific Description
    CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203