Purine riboside triphosphate [23197-96-8]

MedChem Express

Purine riboside triphosphate [23197-96-8]

10

23197-96-8

Research Use Only

C10H15N4O13P3

492.17

Purine riboside-5-O-triphosphate, an active metabolite of Nebularine (HY-103694), acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 microM and 28 microM for the human enzyme, respectively. Purine riboside-5-O-triphosphate also inhibits calmodulin-dependent protein kinase II (CaMKII) with a Ki value of 590 microM[1][2][3].

O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O)N2C3=NC=NC=C3N=C2

12131703