Purvalanol B
HY-18299
Overview
- SupplierMedChem Express
- Product NamePurvalanol B [212844-54-7]
- Delivery Days Customer10
- CAS Number212844-54-7
- CertificationResearch Use Only
- Estimated Purity97.0
- Molecular FormulaC20H25ClN6O3
- Molecular Weight432.90
- Scientific DescriptionPurvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum[1][1].
- SMILESO=C(O)C1=CC=C(NC2=C3N=CN(C(C)C)C3=NC(N[C@@H](CO)C(C)C)=N2)C=C1Cl
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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CAS Number212844-54-7
Estimated Purity98.95%
Molecular Weight432.9
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