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PX-866-17OH [1012327-63-7]

HY-113572
MedChem Express
CAS Number1012327-63-7
Product group Chemicals
Molecular Weight527.61
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PX-866-17OH [1012327-63-7]
  • Delivery Days Customer
    5
  • CAS Number
    1012327-63-7
  • Certification
    Research Use Only
  • Molecular Formula
    C29H37NO8
  • Molecular Weight
    527.61
  • Scientific Description
    PX-866-17OH is the metabolite of PX-866 (Sonolisib, HY-N6775) and a pan-isoform inhibitor of PI3K with IC50s of 14, 57, 131, and 148 nM against PI3Kalpha, PI3Kbeta, PI3K , and PI3Kdelta, respectively[1].
  • SMILES
    C[C@@]12C3=C(C(C(O)=C1/C(C(O[C@@H]2COC)=O)=C\N(CC=C)CC=C)=O)[C@@]4([H])[C@](C[C@H]3OC(C)=O)([C@H](CC4)O)C
  • UNSPSC
    12352200