PXS-5120A [2125955-70-4]

MedChem Express

PXS-5120A [2125955-70-4]

10

2125955-70-4

Research Use Only

98.12

C22H25ClFN3O4S

481.97

PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. PXS-5120A is >300-fold selective for LOXL2 (Ki of 83 nM; pIC50 of 8.4) over LOXL (pIC50 of 5.8)[1].

O=C(C1=CC2=C(N(C/C(F)=C/CN)C(C)=C2C3=CC=CC(S(=O)(N(C)C)=O)=C3)C=C1)O.[H]Cl

2°C to 8°C

12352200