PXS-5153A [2125956-82-1]

MedChem Express

PXS-5153A [2125956-82-1]

10

2125956-82-1

Research Use Only

C20H25Cl2FN4O2S

475.41

PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of IC50 of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.

CC(N1C/C(F)=C/CN)=C(C2=CC=CC(S(N(C)C)(=O)=O)=C2)C3=C1C=CC=N3.Cl.Cl

12352200